Hwang Lab

Assembling biology one molecule at a time



We use multidisciplinary techniques combining single-molecule to cell imaging, biochemistry and synthetic biology to study the molecular mechanisms of chromosome organization and bacterial cell division. We are interested in understanding how bacteria, despite their small size and lack of obvious cytoskeleton, are able to spatially organize genomic DNA and proteins to specific locations in the cell. These bacterial positioning systems form distinctive patterns within the cells, and are involved in important cellular functions such as chromosome segregation, cell division and motility.


Bacterial cell division

Chromosome Dynamics

Cell-free reconstitution

Optical Microscopy



Ling Chin Hwang

Principal Investigator

Adam Brooks

PhD student

Satpal Chodha

PhD student

Alexandra Parker

PhD student

Join Us

Dr. Ling Chin Hwang
University of Sheffield
Department of Molecular Biology and Biotechnology
Firth Court
Western Bank
Sheffield S10 2TN, UK

+44 (0)1142 222847


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